Budesonide
The dose should be given twice daily.
Administration once daily may be considered in cases of mild to moderate stable asthma.
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1.Composition
Budesonide 0.5mg/2ml
2.Dosage Form
Nebulizer suspension
3.Indication
Treatment of asthma and as prophylactic therapy
4.Dosage Administration
Asthma
The dose should be given twice daily.
Administration once daily may be considered in cases of mild to moderate stable asthma.
Initial dosage:
The initial dose should be tailored to the severity of the disease and thereafter should be adjusted on an individual basis. The following doses are recommended but the minimum effective dose should always be sought:
Children aged 6 months and above: 0.25 – 1.0mg daily. For patients in maintenance therapy with oral steroids a higher initial dosage up to 2.0 mg daily should be considered.
Adults (including the elderly) and children/adolescents over 12 years of age: 0.5 - 2 mg daily. In very severe cases the dosage may be increased further.
Maintenance dose: The maintenance dose should be adjusted to meet the requirements of the individual patient taking account of the severity of the disease and the clinical response of the patient. When the desired clinical effect has been obtained, the maintenance dose should be reduced to the minimum required for control of the symptoms.
Children aged 6 months and above:0.25 - 1.0mg daily.
Adults (including the elderly) and children/adolescents over 12 years of age: 0.5 - 2.0mg daily. In very severe cases the dose may be further increased.
Administration once daily:
Administration once daily should be considered for children and adults with mild to moderate stable asthma and with a maintenance dose between 0.25 mg and 1 mg budesonide daily. Once-daily administration may be initiated both in patients who are not receiving corticosteroid treatment and in well-controlled patients who are already taking inhaled steroids. The dose may be given in the morning or evening. If a worsening of the asthma occurs, the daily dose should be increased by administering the dose twice daily.
Onset of effect:
An improvement of the asthma following administration of budesonide may occur within 3 days after initiation of therapy. The maximum effect will only be obtained after 2-4 weeks of treatment.
